SINGAPORE: Antagonistic results after receiving the bivalent COVID-19 vaccine pictures are uncommon, based on a Well being Sciences Authority (HSA) security replace launched on Thursday (Feb 2).
The authority acquired 59 and 11 hostile occasion experiences for the Moderna/Spikevax COVID-19 bivalent vaccine and Pfizer-BioNTech/Comirnaty COVID-19 bivalent vaccine respectively.
Greater than 482,600 doses of the Moderna bivalent vaccine have been administered because it was rolled out in Singapore on Oct 14 final 12 months, whereas greater than 202,300 Pfizer-BioNTech bivalent jabs have been given since Dec 12, 2022.
This implies the HSA noticed an hostile occasion reporting fee of 0.012 per cent for the Moderna bivalent vaccine and a smaller 0.005 per cent for the Pfizer-BioNTech bivalent vaccine.
The hostile occasions reported for the bivalent mRNA vaccines had been related to people who took the monovalent vaccine. The non-serious hostile occasions embrace allergic reactions similar to a rash, eyelid swelling, fever, giddiness, chest discomfort or a rise in blood strain.
There have been additionally six severe hostile occasions reported for the Moderna bivalent vaccine and two such occasions for the Pfizer-BioNTech bivalent vaccine.
These embrace severe allergic reactions, anaphylaxis, myocarditis, hypotension with tachycardia – quick heartbeat – and listening to loss, stated HSA.
An hostile occasion is assessed as severe when it resulted in hospitalisation, a major discount in functioning stage, a life-threatening sickness or loss of life.
The intense hostile occasions reporting charges for the 2 bivalent vaccines are related, at 0.001 per cent.
HSA’s newest replace covers the interval from the roll-out of the vaccines on Dec 30, 2020, to Dec 31, 2022. That is the primary HSA security replace to incorporate knowledge on the bivalent pictures.
Together with the monovalent mRNA vaccines, greater than 10.5 million major doses, 4.6 million first booster doses and 1.2 million second booster pictures have been administered in Singapore as of Dec 31, 2022.
The reporting charges of hostile and severe hostile occasions for the mRNA vaccines remained uncommon, at 0.11 per cent (17,741 experiences) and 0.007 per cent (1,119 experiences) respectively.
There have been 173 severe hostile occasion experiences (0.004 per cent) for the primary booster jab and 17 such experiences (0.001 per cent) for the second booster shot.
ADVERSE EVENTS IN CHILDREN
The Moderna vaccine was rolled out on Oct 25 final 12 months as a major vaccine for youngsters aged six months to 4 years, whereas the Pfizer-BioNTech jab was additionally made accessible as a booster for youngsters aged 5 years to 11 years.
As of Dec 31, 2022, greater than 16,000 doses of the Moderna vaccine have been administered to youngsters aged six months to 4 years, and greater than 81,000 Pfizer-BioNTech booster jabs have been given to youngsters aged 5 years to 11 years.
Severe hostile occasions after COVID-19 vaccination in youngsters aged six months to 11 years are uncommon, stated HSA.
There have been eight hostile occasion experiences after youngsters aged six months to 4 years who took the Moderna jab, together with 5 severe occasions that included fever, vomiting, matches, and Kawasaki illness – the swelling of blood vessels.
“Febrile seizures and Kawasaki disease are rare events that have been reported following childhood vaccination and can be associated with childhood illnesses. All the children have recovered or were recovering at the time of report,” stated HSA.
There have been 26 hostile occasion experiences from the Pfizer-BioNTech booster jab for youngsters aged 5 years to 11 years – a reporting fee of 0.03 per cent. This was decrease than the hostile occasion reporting fee for the first vaccination collection on this age group, which stood at 0.15 per cent.
There have been additionally two severe hostile occasions, with one describing myocarditis – the irritation of coronary heart muscle mass – and the opposite was a drop in platelet depend.
Each youngsters had been recovering on the time of the report, stated HSA.
#asiannews #asian_news
